Pain, frequent burning, loss of sensation, cramps, weakness, hyper-sensitivity and other symptoms are part of the syndrome.
Symptoms that suggest neuropathy include pain, pins and needles, numbness, increased sensation to touch cramps weakness and difficulty with balance.
These occur most commonly in the feet and hands, and progress to involve the entire limb. They can be present either during activity or quite commonly at rest.
Known causes of neuropathy include diabetes, compression of nerves in both upper and lower limbs (carpal/tarsal tunnel syndromes), HIV infection and cancer chemotherapy among others. Pain in some of these disorders can be difficult to treat.
That’s why the Chicago Peripheral Nerve Center specializes in the most advanced and state-of-the-art treatments for pain associated with:
In addition, the center treats other neuromuscular disorders, spinal and chronic pain in general (neck and back).
The best time to treat Neuropathy and its symptoms is today. If you are suffering from the pain and symptoms associated with Neuropathy contact the Chicago Peripheral Nerve Center today: 888.299.8405
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Dr. Roberto P. SeguraDr. Roberto P. Segura was a member of NMFF (Northwestern Medical Faculty Foundation) and director of EMG Laboratories and the Neuromuscular Program at Northwestern in the Neurology Department between 1977 and 1990. He subsequently joined the Chicago Institute of Neurosurgery and Neuroresearch (CINN) as Director of Neurology and Neurodiagnostics. Dr Segura serves as co-chairman of the Latino American Diabetes Association. |
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Dr. Edgardo R. RodríguezDr. Segura's Partner, Dr. Edgardo R. Rodríguez, is specially trained in the surgical decompression of lower limb entrapment neuropathies. He also specializes in complex foot disorders, deformity correction such as Charcot's joint and injuries of the lower leg, ankle and foot. For further information on Dr Rodriguez please visit www.cfaas.com. |

Symptoms that suggest neuropathy include pain, pins and needles, numbness, increased sensation to, touch, cramps weakness and difficulty with balance. These occur most commonly in the feet and hands, and progress to involve the entire limb. They can be present either during activity or quite commonly at rest.
A high percentage of the population suffers from neuropathy and majority have diabetes. Diabetes is the most common cause of peripheral neuropathy. In the United States, an estimated 17 million people have diabetes, although this is an underestimate since the disease remains undiagnosed in approximately half. Over 60% of diabetics will develop noticeable evidence of neuropathy and most diabetics will have variable forms during their lifetime.
Neuropathy may occur early in the disease during the stage of impaired glucose tolerance called prediabetes.
Disability caused by neuropathy is common in diabetes because of frequent severe burning pain. The most common cause of ulceration of the foot and amputation is diabetic neuropathy.
Call Today To Schedule a Consultation *888.299.8405*
I was a physically active individual until about six years ago. I spent the late 50s and the 60s very involved in synchronized swimming. In the eighties I trained for four marathons (26.2 miles) and completed two of them. I jogged daily. I enjoyed careers as a middle school teacher and a clinical social worker. I served on my local school board. I skied. About six years ago, shortly after turning sixty, I began to experience serious mobility problems, frequent loss of balance and some falls. My stamina for walking and standing became limited. I refused to allow myself to become dependent on a cane or walker.
I was referred to Drs. Roberto Segura and Edgardo Rodriquez by Dr. Arnold Grauer, my internist, during my annual physical. Dr. Grauer asked me if I wanted to see a doctor who specialized in peripheral neuropathy. I was more than willing to see a specialist after more than six years of numbness, tingling, burning, and muscle weakness that began in both feet and eventually moved up and down each leg. I had had two years of Neurontin and two years of Lyrica without significant relief from what became chronic acute symptoms. My then neurologist had talked about needing to find the cause of the neuropathy, but he also told me that there was really nothing more he could do besides prescribing medication for the symptoms. He did two EMG tests on my legs about a year apart, and did an ultrasound on my legs to check circulation. My symptoms were always worse in cold weather, but in the summer of 2011 I began to have the same problems in warm weather that I usually had in cold weather. I began to fear that I would eventually not be able to walk without assistance or even be confined to a wheelchair. In addition to medication I also tried acupuncture, chiropractic treatments, regular massages and Tai Chi to relieve the pain, burning, and muscle cramps. Relief from symptoms was only temporary.
My first appointment with Dr. Segura was very encouraging. After hearing the history of my symptoms, he did a different kind of test on each leg, a nerve conduction velocity (ncv) test. He also ordered a glucose tolerance test to rule out diabetes as a cause for my symptoms. The GTT confirmed that I am not diabetic, but Dr. Grauer advised me to limit carbohydrates and sugar intake. Dr. Rodriquez examined my legs and used ultrasound to determine if there was anything inside my legs causing my symptoms. He administered nerve block injections in each leg to see if the pain was relieved; it was, but only for about 24 hours. After three appointments with Drs. Segura and Rodriquez, plans were made for outpatient surgery to release the entrapped nerves in each leg. Dr. Rodriquez stated that I should experience 60% improvement in symptoms after the surgery.
My surgery was December 16, 2011. I came to the hospital with extreme pain along both legs—muscle cramps, burning, tingling. I woke up after surgery with NO PAIN except around the three incisions on each leg!!!! I am now regaining my mobility and leg strength only four weeks after surgery. The staples were removed after three weeks, and the stitches will be removed after six weeks. Not only was my surgery successful beyond my hopes, but the care I received from Dr. Rodriquez was exceptional. He has called, sent text messages, and proudly exclaimed about the results from my surgery. Information has been regularly shared with Dr. Seguro and with Dr. Grauer. What a contrast to my previous neurologist! I am elated with my progress to date and look forward to working with a physical therapist to increase my leg strength in the coming weeks.
I urge anyone who has experienced this debilitating condition to seek out Drs. Roberto Segura and Edgardo Rodriquez across from the Northwestern hospital campus.
Barbara D. Leek
Throughout 2011, I experienced severe pain, tingling and loss of sensation in my feet, balance issues and hypersensitivity. My symptoms worsened at night or whenever my feet were elevated, and subsequently my sleep pattern suffered. I was concerned about not being able to maintain my active lifestyle and exercise program, and so attended the Chicago Peripheral Nerve Centre for assessment and examination. Dr Segura carried out an EMG/NCV test to confirm the presence of Peripheral Neuropathy, whilst an MRI enabled Dr Rodriguez to diagnose Tarsal Tunnel Syndrome in both of my legs. Both doctors attended my reviews and follow-up appointments, and their working relationship, combined knowledge and technological resources resulted in an accurate diagnosis and speedy treatment solutions. Double leg surgery was recommended, and quickly arranged. Dr Rodriguez’s surgical team were excellent and I was kept well informed at every stage. The surgery went smoothly and, though still healing, I am now well on my way to making a full recovery. Meanwhile, my symptoms are noticeably improved. Dr Rodriguez’s aftercare program continues to be professional and exceptional. He pays full attention to his patients throughout their recovery period. He communicates with them on a daily basis and follow-up appointments are carried out to schedule. Any of my own personal concerns are promptly addressed with either a telephone call or during a same-day visit to his office. I continue to need follow-up appointments to monitor my progress, but I am very happy to continue my treatment and recovery program with the help of the Chicago Peripheral Nerve Centre.
Jenny Gill
Roberto Segura. Incidence of Tarsal Tunnel Syndrome in a Diabetic Population
Rodriguez E et al. Peripheral Nerve Blocks with 0.5% Bupivacaine for the Treatment of Tarsal Tunnel Syndrome and Peripheral Neuropathy in Diabetic Patients. Prospective Study in 28 patients
Symptomatic Subtalar Joint Pathology Treated with Deep Peroneal Neurectomy
Another common form of peripheral nerve involvement seen mostly in long standing disease is autonomic neuropathy or dysfunction of the "involuntary" nerves. It may cause sweating disturbances (loss of sweat), low blood pressure, slowed digestion, diarrhea, bladder problems and cardiac arrhythmias. Erectile dysfunction is common, with impotence occurring in 20-60 % of diabetic men.
Diabetic neuropathies can also present with severe mid to low back pain, weakness and atrophy of the thigh muscles, paralysis of muscles in the face and profound weight loss associated with severe pain in the distal limbs and back , depression and impotence in men.
Compression of nerves in arms or legs is very common in diabetics, specially at the level of the wrist and ankle (carpal tunnel syndrome and tarsal tunnel syndrome). Nerves that travel through fibroosseous tunnels are more sensitive to compression. This problem can cause significant difficulties using the hands or walking.
Symptoms that resemble diabetic neuropathy can be seen in other conditions like HIV infection or the effect of multiple medications that are used in the treatment of cancer.
Pain in neuropathy is the most disabling symptom and requires special attention.Medication should be tried first. The drugs that may be effective in some cases include antidepressants, anticonvulsants and opiates or similar substances. Unfortunately their use is limited by significant side effects in many instances. Topical agents in the form of creams have also been tried.
Physical modalities include TENS units, ultrasound and lately, a form of infrared photo energy device applied to the skin of the painful area (monochromatic infrared energy or MIRE).
If these treatment approaches fail to relieve disabling symptoms, decompressive surgery can be performed. This involves releasing the pressure on the affected nerves. The most common areas of compression are the wrist (carpal tunnel syndrome), the ankle (tarsal tunnel syndrome), and other nerves in the arm and leg including the foot.
Relief or improvement in pain and restoration of sensation has been achieved in about 85% of cases (J Am Podiatr Med Assoc 95(5): 451-454, 2005).
Surgical decompression can also prevent serious complications of the foot like ulcerations and ultimately amputations.
The diagnosis of neuropathy requires a careful and detailed history and examination. This should be complemented by electrodiagnostic studies (NCS/EMG) and in early cases with quantitative sensory testing to detect alterations of touch, vibration and temperature.
Additional information may be obtained with the use of ultrasound and skin biopsies to detect early nerve damage.